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| Carneiro,Jaqueline; Döll-Boscardin,Patrícia Mathias; Fiorin,Bárbara Celânia; Nadal,Jessica Mendes; Farago,Paulo Vitor; Paula,Josiane Padilha de. |
| ABSTRACT Skin aging causes changes such as wrinkles and flaccidity leading to a large demand for aesthetic procedures, including dermal filling. A key agent in dermal filling is hyaluronic acid (HA), which is a naturally occurring glycosaminoglycan. However, it is a hydrophilic macromolecule that experiences great difficulty in crossing the skin barrier causing most commercial formulations containing it to be injectable, which in turn brings risks since they involve an invasive technique. In that sense, the aim of this study was to develop and characterize nanoparticles obtained from ionic interaction between HA and lysine (Lys) for use as a potential agent of dermal filling for topical application, increasing and improving its applicability and safety. To... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nanotechnology; Skin aging/non-invasive method; Skin aging/treatment/study.. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000400645 |
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| Gonçalves,Melissa Marques; Carneiro,Jaqueline; Justus,Barbara; Espinoza,Joel Toribio; Budel,Jane Manfron; Farago,Paulo Vitor; Paula,Josiane Padilha de. |
| Antibacterial activity and good mechanical properties are some of the characteristics required for an appropriate film dressing. A novel polymer blend was developed for wound healing application. Twenty-four formulations using the polymers chitosan, poly(vinyl alcohol) and/or ɛ-Polylysine and the plasticizer glycerol were designed using factorial design and then the films were prepared by the casting/solvent evaporation method. Seventeen films were obtained among the twenty-four proposed formulations that were characterized by Field Emission Scanning Electron Microscopy (FE-SEM) and Fourier Transform Infrared Spectroscopy (FTIR). Mechanical properties, such as tensile strength (σ), elongation at break (ɛ) and Young’s modulus (Y) as well as antibacterial... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chitosan; Poly(vinyl alcohol); Ɛ-Polylysine; Semi-occlusive dressing. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100631 |
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